Session Schedule

Find a specific presentation in the session by navigating to the timestamp indicated below.

0:00:00
Introduction

0:01:20
Association between the incidence of major adverse cardiovascular events and the presence of obstructive sleep apnea
Ronald Lee (Singapore)

0:24:50
The relationship between sleep duration and glucose metabolism
Sirimon Reutrakul (United States)

0:51:00
The prevalence of insomnia in Asia and its association with the increased risks of cardiometabolic diseases
Naricha Chirakalwasan (Thailand)

1:15:00
The effect of environmental components in shaping sleep quality and duration
Motoo Yamauchi (Japan)

Summary

Cardiometabolic diseases, including diabetes, hypertension, and cardiovascular disorders, are a growing public health challenge in Asia due to rapid urbanization, sedentary lifestyles, and obesity epidemic. Concurrently, sleep disorders such as obstructive sleep apnea, insufficient sleep syndrome, and insomnia are on the rise and have been increasingly recognized as critical contributors to cardiometabolic risk. This symposium explores the interplay between sleep disorders and cardiometabolic diseases from an Asian perspective, focusing on unique regional factors, genetic predispositions, and lifestyle influences.
Ronald Lee, MD (National University of Singapore, Singapore) will present the association between the incidence of major adverse cardiovascular events post-PCI and the presence of obstructive sleep apnea, suggesting that obstructive sleep apnea contributes to poorer cardiovascular outcomes in these patients. There is also data on the high prevalence of obstructive sleep apnea among acute myocardial infarction patients and specific predictors for obstructive sleep apnea have been identified in this population. Importantly, the presence of obstructive sleep apnea was linked to impaired microvascular perfusion, indicating a potential mechanism by which obstructive sleep apnea exacerbates cardiac injury during acute myocardial infarction.
Sirimon Reutrakul, MD (University of Illinois Chicago, U.S.A., and Mahidol University, Thailand), will discuss on the relationship between sleep disturbances and glucose metabolism. Insufficient sleep syndrome adversely affects glucose regulation, increasing the risk of insulin resistance and type 2 diabetes. Furthermore, there is current evidence that explored the effects of sleep extension on glucose and energy metabolism. In habitual short sleepers, there is data demonstrating that extending sleep duration potentially improves insulin sensitivity, suggesting that increasing sleep duration may benefit glucose metabolism in individuals at risk for diabetes. The latest pilot data on the effects of cognitive behavioral therapy for insomnia on glucose metabolism and patient-reported outcomes in Asian persons with type 2 diabetes will be presented.
Naricha Chirakalwasan, MD (Chulalongkorn University, Bangkok, Thailand) will highlight the prevalence of insomnia in Asia and its association with the increased risks of hypertension, type 2 diabetes, and obesity. Rapid urbanization, socio-cultural factors, and high levels of occupational stress contribute to the growing prevalence of insomnia. There are a few insomnia guidelines in Asia and the main treatment includes cognitive behavioral therapy for insomnia (CBT-i) and pharmacological therapy. Due to limited availability of CBT-i, current evidence demonstrated that internet based CBT-i is a comparable alternative option for insomnia therapy.
Lastly, Motoo Yamauchi, MD (Nara Medical University, Nara, Japan) will discuss on the effect of environmental components including light exposure, noise pollution, air quality, temperature, and urban living conditions in shaping sleep quality and duration. For example, the exposure to light during sleep increased sympathetic nerve activity and worsened sleep-disordered breathing in healthy individuals, suggesting that sleeping in a lighted environment may negatively affect cardiovascular health.